ENCyclopedia Of DNA Elements (ENCODE)

The goal of NHGRI’s ENCODE project is to identify and develop technology to identify all functional elements in the recently completed human genome sequence. To accomplish this NHGRI has funded a collection of different groups to examine, in detail, 1% of the human genome sequence. These groups are employing various experimental and computational techniques to identify regulatory sites within the DNA sequence.

As part of the Stanford ENCODE project, led by Dr. Richard M. Myers, we are examining ancestral polymorphisms in highly conserved non-coding sequences. These targets were selected by comparing the ENCODE regions of human sequence to the available sequence from other organisms and finding sequence that many species have in common.

More information will be added about this project as it becomes available.